AOAC 998.10 tests the preservation of cosmetic and toiletry formulations by introducing microbes into the product and measuring surviving organisms over time. Preservation testing determines the resistance of the test sample to the growth of microorganisms and is an important part of product performance testing. Microbes may be contained during the production of a product, however, […]
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The ASTM D5660 test method is the legacy standard test method for assessing the microbial detoxification of chemically contaminated water and soil using a toxicity test with a luminescent marine bacterium, Photobacterium phosphoreum. Testing provides valuable information on how a chemical may contaminate water or soil while in use and after disposal. Sensitive environments can be greatly affected by even […]
ASTM D5660 – Phototoxicity Testing
ASTM D93 determines the flash point of a test substance by a Pensky-Martens closed-cup apparatus. Flashpoint is the lowest temperature at which an ignition source causes the vapors of the test sample to ignite under specified conditions of the test. The flash point temperature then determines the tendency of the test specimen to form a flammable mixture with air when under these […]
ASTM D93 – Flash Point Test
ASTM E640 is a standard preservation test method for testing performance of preservatives found in water-containing cosmetics. ASTM E640 Commonly used for personal care and cosmetic products where the use of an effective and long-lasting preservative is a key consideration in formulation development, storage, and continual use. ASTM E640 is a multi-cycle challenge test that exposes a […]
ASTM E640 – Preservation Test – Cosmetics
ISO 11734 is a solution anaerobic biodegradation test that evaluates ultimate anaerobic biodegradability of organic compounds in digested sludge. Measurement for analysis for ISO 11734 is done by biogas production. The ISO 11734 test method applies to organic compounds with a known carbon content and are: Soluble in water, or Poorly soluble in water, provided exact dosing […]
ISO 11734 – Anaerobic Biodegradation
ISO 14593 is a solution biodegradation test that performs an evaluation of ultimate aerobic biodegradability of organic compounds in an aqueous medium. Ultimate aerobic biodegradation: Microorganisms fully consume a chemical compound or organic matter by in the presence of oxygen. Produces carbon dioxide, water and mineral salts. The ISO 14593 method analyzes inorganic carbon in sealed vessels (CO2 headspace test). It […]
ISO 14593 – Ultimate Aerobic Biodegradation
OECD 105 determines the water solubility of a substance. OECD 105 determines the water solubility of essentially pure substances which are stable in water and not volatile. It is important to note that the presence of impurities can considerably affect the water solubility of a substance. It is recommended to have preliminary information on the test substance’s structural […]
OECD 105 – Water Solubility
OECD 111 assesses abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). OECD 111 is an important evaluation for determining how a chemical will react in an aqueous environment; hydrolysis itself is an important reaction controlling degradation. Abiotic hydrolysis is likely one of the most common […]
OECD 111 – Hydrolysis as a Function of pH
OECD 113 is a preliminary assessment to evaluate the stability of a substance with respect to heat and air. OECD 113 is commonly used to determine stability and is used as guidance in the performance of other tests. The determination of storage stability is applicable to homogeneous solid and liquid substances and to mixtures of these. Two principle test methods […]
OECD 113 – Thermal Stability and Stability in Air
OECD 121 estimates the adsorption coefficient on soil and sewage sludge using high-performance liquid chromatography (HPLC). The adsorption coefficient (Koc) determines the tendency of a chemical to bind to soils or sewage sludge. The binding capacity of a chemical on organic matter of soil and sewage sludge allows comparisons to be made between different chemicals through their adsorption behavior. The […]
OECD 121 – Adsorption Coefficient using HPLC
OECD 201 is a standard freshwater algae and cyanobacteria Growth inhibition test commonly used for aquatic toxicology testing. OECD 201 determines the effects a substance has on the growth of freshwater micro-algae or cyanobacteria through an acute aquatic plant growth toxicity test. OECD 201 exposes exponentially growing organisms to the test substance over a 72 hour test […]
OECD 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test
OECD 202 is an acute immobilization toxicology test that determines the concentrations of a material that immobilizes Daphnia species. Standard testing for OECD 202 is performed by exposing young daphnids to the test substance at a range of concentrations for a period of 48 hours. Immobilization is recorded at 24 hours and 48 hours and compared with […]