Upcoming Expo &
Technical Conference
847­-483-9950

OECD 105 – Water Solubility

OECD 105 determines the water solubility of a substance.OECD 105 determines the water solubility of a test substance by analytical analysis

OECD 105 determines the water solubility of essentially pure substances which are stable in water and not volatile. It is important to note that the presence of impurities can considerably affect the water solubility of a substance.

Additionally, it is strongly recommended that before determining water solubility, some preliminary information on the substance like structural formula, vapor pressure, dissociation constant and hydrolysis as a function of pH is communicated with the test laboratory. Customer commonly request OECD 112 to determine the Dissociation constant and OECD 111 for the Hydrolysis as a function of pH.

OECD 105 is commonly requested to analytically determine water solubility of a material for product development and to determine solubility performance.  OECD 105 is used to determine water solubility and can be used in companion with the Water Accommodated Fraction determination of a material that is recommended for poorly soluble and insoluble materials undergoing biodegradability testing.

OECD 105 and other analytical tests that evaluate a material’s chemical and physical properties are commonly used for product registration, such as EPA Pesticide registration that is outlined in 40 CFR Part 158, Data Requirements for Registration, and to meet regulatory requirements. When testing for regulatory purposes, it is highly recommended to review testing requirements with the appropriate regulatory agency prior to testing.

For more information on water solubility and Analytical testing, contact our analytical laboratory at 847-483-9950 or info@situtest.com.

Situ Biosciences is Exhibiting in the Advanced Textiles Testing Demo Zone!

@ IFAI Expo 2017

September 26-29, 2017
New Orleans, LA

laboratory glassware on white

Let us know if you’d like to have a meeting at the conference!

847-483-9950 – info@situtest.com